Lady Gaga thinks Kelly Osbourne’s talk show “breeds negativity”.

The 26-year-old songstress is known for her crusade against bullying and launched the Born This Way Foundation with her mother in 2012 to combat the practice.

Last year Kelly told British magazine Fabulous that “Gaga’s fans are the worst.” She claims the singer’s “Little Monsters” have even suggested that the Fashion Police host commit suicide.

Newly thin Kelly recently lost a significant amount of weight, and in an open letter posted and then later removed on her website, Lady Gaga urged Kelly to be more positive on her talk show.

" 'Appearance' is the most used reason for bullying in the world. Your show breeds negativity, and over the years has even become comedic in nature," Gaga penned.

"It glorifies you and Joan Rivers pointing in the camera, laughing, and making jokes about artists and celebrities as if we are zoo animals. What about your body revolution? It used to make me truly sad when I would hear people talk about your weight when you were younger, as I was bullied too. To see you blossoming into a beautiful slender woman who makes fun of others for a living is astounding. Why not help others? Why not defend others who are bullied for their image and share your story?"

In response to the negative comments about her weight gain last autumn, Gaga launched web campaign entitled A Body Revolution 2013.

Body Revolution urged people to embrace their figures.